Monday, December 1, 2008

WOMEN WITH SHORT LEGS MAY HAVE A HIGHER RISK OF LIVER DISEASE

WASHINGTON (Reuters)

Women with short legs may have a higher risk of liver disease, probably caused by either diet or other factors early in life, British researchers reported on Monday.


Their study of 3,600 women showed that the shorter a woman's legs were, the more likely she was to have signs of liverdamage.

The findings fit in with other studies linking leg length with diabetes and heart disease, Abigail Fraser of the University of Bristol and colleagues said, "Adult liver function is affected by early life environmental exposures as reflected in leg length, and this may suggest common childhood influences on liver development and adult risk of diabetes and coronary heart disease," they wrote.


Fraiser's team looked at women aged 60 to 79 who were taking part in a larger health study.They measured their leg length as compared to trunk length and also measured four liver enzymes: alanine aminotransferase, gamma-glutamyltransferase, aspartate transaminase and alkaline phosphatase. "Each of these markers reflects a different aspect of potential liver damage," they wrote in their report, published in the Journal of Epidemiology and Community Health.


Leg length can point to how well a person was nourished in early childhood. "In particular, evidence shows that breast-feeding, high-energy intake at four years and childhood affluent socioeconomic position are all associated with longer adult leg length," Fraser's team wrote.


The findings held even when Fraser's team took into account smoking, drinking and other behaviours that can damage a person's liver. (Reporting by Maggie Fox; editing by Mohammad Zargham).


How To Protect Yourself Against Liver Damage

A study published in the July 5th, 2006 edition of the Journal of the American Medical Association indicates that taking the maximum recommended dose of Tylenol (acetaminophen) for fourteen consecutive days can cause acute liver damage.


Medical researchers who co-ordinated this study had 106 participants take 4 grams of acetaminophen (the equivalent of eight 500 mg tablets of extra-strength Tylenol) every day for two weeks.


Thirty-nine participants received placebo pills.The key results were as follows:Among the participants who took acetaminophen, almost 40 percent showed signs of acute liver damage.Those who showed signs of acute liver damage continued to show signs of liver stress four days after they stopped taking acetaminophen; it took a full eleven days for their liver enzymes to return to normal levels.


Why is your liver so susceptible to damage by acetaminophen? Because almost everything that enters your mouth, travels down your digestive tract, and gets absorbed into your blood stream must travel directly to and through your liver before it travels through the rest of your circulatory system.Your liver acts as a processing plant. It receives everything that you put into your mouth and that ends up in your blood stream, does its best to sort out useful nutrients and harmful substances, and then packages these nutrients and harmful substances to be delivered to your cells and eliminated from your body, respectively.

When certain drugs like those that contain acetaminophen reach your liver for processing, they can cause direct injury to your liver cells, sparking an inflammatory reaction that leads to increased production of liver enzymes, which a standard blood test can detect.


If your liver cells are injured repeatedly, they can go through a series of degenerative changes, the last ones being cirrhosis (hardening) and cancer of the liver.


Medical drugs that list liver damage as a potential "side" effect and all forms of alcohol are the two groups of substances that can most efficiently and predictably cause liver damage in the fashion described above.


Protecting yourself against liver damage must begin with avoidance of said medical drugs (whenever possible and under the guidance of your doctor) and alcohol.


It's true that not everyone who takes medical drugs and drinks alcohol regularly over many years ends up with irreversible liver damage. Genetics and lifestyle changes can help to ward off liver damage despite a history of alcohol and drug use. Still, you should be aware that any amount of these two substances can and do heap unnecessary stress onto your liver cells.


Beyond doing your best to avoid drugs and alcohol, here are some additional steps that you can take to protect yourself against liver damage:Stay away from foods that are high in unhealthy fats and/or sugar. Donuts, deep fried fast food, and soda are three of the worst foods for your liver. And yes, chicken McNuggets and McChicken sandwiches are deep fried.Eat mainly fresh, minimally processed foods. Focus on green vegetables and produce that comes in rich colors like field tomatoes, carrots, avocado, mango, blueberries, and blackberries. These richly colored fruits and vegetables contain naturally occurring antioxidants that can help to protect your liver cells against physical injury.


Use extreme caution and common sense when it comes to being physically intimate with another person. Hepatitis B and C are viruses that can cause significant liver damage. These viruses live in all body fluids, including blood and seminal fluids.Be aware that hepatitis C is most commonly spread via blood, and can be acquired through contaminated needles used for IV drug injections, body piercing, and tattooing.


Strive to stay away from chemicals of all types, particularly pesticide and insecticide sprays, which can inflict direct damage to your liver cells once they make their way into your blood stream. Many chemicals are capable of entering your blood stream through your skin, so try to use on your skin only those products that you feel comfortable eating.

One final note: if you rely on regular intake of acetaminophen to deal with intolerable pain, I encourage you to try taking a high quality cod liver oil or fish oil for their omega-3 fatty acids, which can be extremely effective at decreasing inflammation.


Tasly products to help you have a healthier liver:


Tasly Cerebral Care Granules

Tasly Cerebralcare Granules is a new generation herbal food supplement which Improves
Mental alertness - Revives vital energy
It is beneficial for overcoming various types of headache, improves soft brain membrane micro-circulation, increases blood flow to the brain and prevents vascular spasm.




INDICATIONS
Its main indications being preventing headache due to hypertension, tension due to stress, menopausal headache, periodic headache, migraine and etc.

In other word, it is excellent for relieving various headaches by dual effects (overcoming the cause and symptom as well) and rapidly improving micro-blood circulation in the brain. Thus effectively reduces occurrence of headache.

I

Specification: 4g X 20 sachets
Dosage: 1 sachet per time, 1 to 2 times per day, taken with lukewarm water
Accreditation:Cerebralcare Granules had the China National New Medicine Certificate in 1996. While in 1999, it has been listed in China National Fundamental Medicine Catalogue.
In the same year, the product received National Invention Patent and a year later in 2000; it was listed in the National Protective Medicine Catalogue.


Tasly Omega-3 Fatty Acid Capsule


Has been proven to be vitally important in human health, growth and development. Generally speaking, their functions in human body include:

1. Omega-3 is an essential part for the cellular membrane to remain function. A shortage of Omega-3 reduces the ability of cells to efficiently perform their

functions, accordingly leads to nutrient starvation and chronic illnesses.

2. Eicosanoids, the most critical of which are prostaglandins, are also converted by Omega-3. Prostaglandins are important for the regulation of inflammation, pain, blood pressure, heart function, gastrointestinal function and secretions, kidney function transmission, steroid production and hormone synthesis. Lacking or unbalanced of Omega-3 leads to dysfunction of these vital bodily activities.

3. DHA has been identified as an essential building block of brain, nerve and eye tissue. It is especially important to the development of an infant's visual acuity.

4. EPA diminishes inflammation and blood clots within the cardiovascular system.

5. DPA, as the effective agent, is almost as important as either DHA or EPA

Tasly Omega-3 Fatty Acid Capsule refined from Harp seal Oil includes the essential fatty acid Alpha-linolenic acid and its longer chain metabolites (DHA-Docosahexaenoic Acid, DPA-Docosapentaenoic Acid & EPA- Eicosapentaenoic Acid). And that has more DPA which is special in protecting and repairing blood vessels, reducing coronary artery diseases of women. People of all ages can benefit from it.

Nutritional Information: Each capsule (500mg) contains DHA 210mg, EPA 180mg, DPA 90mg, which is refined from Harp Seal Oil.
Dosage: 1 Capsule, two times a day

                



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TASLY CARDIOTONIC PILL: IMPROVING YOUR HEART AND BLOOD MICROCIRCULATION SYSTEM

Go downIs a Chinese herbal product that is one of the top selling herbal products sold in China for heart health. Dan Shen (Salviae Mitiorrhizae), Cardiotonic Pill main herb, first appeared in China’s “Shen Nong Herbal Classic” and has been clinically used for decades as a blood moving herb in promoting circulation.

Combined with other blood moving and Qi tonifying herbs, Cardiotonic Pill or Danshen Plus Capsule is a convenient, alternative therapy for heart health based on Traditional Chinese Medicine principles and modern day research.

Its droplet pill formulation offers many advantages such as low dosage, rapid and complete absorption, fast onset of action, high potency and convenience.


Tasly Cardiotonic Pill

Main Ingredients:
Dan Shen (Salviae Mitiorrhizae)
San Qi (Panax Notoginseng)
Huang Qi (Astragalus membranaceus)
Jiang Xiang (Dalbergiae Odoriferae)

Suggested Use:

Take 1 pill orally three times per day. The effect was achieved faster when taken under the tongue, let dissolve in mouth and swallow. Improvement for healthy heart function has been seen after only 2-4 weeks.

The Dripping Pill, a Prevalent Dosage Form for Higher Bioavailability:

Innovation in herbal medicine can be found throughout the world these days, and there is no better example of manufacturing and dosage vicissitude than the dripping pill, manufactured by Tasly Pharmaceutical Co., Ltd., one of the top five largest pharmaceutical companies in China.

The Dripping Pill is a rapidly developing form of Chinese herbal medicine, prepared by blending an herbal extract and a matrix under thermal conditions and dripping the mixture into a cooling liquid in which the droplets are insoluble. The process of pill formation results in a solid-dispersoid in a pill shape.

Characteristics of the Dosage Form:

Dripping pills are a promising dosage form. The process of formation is similar to that of preparing a solid dispersoid by melting. Melting herbal extract and matrix together make the botanical molecules disperse evenly throughout the matrix, and when congealed to from a eutectic solution, both herbal extract and the matrix molecules turn into very fine, tiny crystals. These crystals are easily absorbed with a higher bioavailability, rapid biological activity and lower adverse effects compared with conventional dosage forms such as, tablets and capsules. This helps promote stability of the herbal extract. Fine crystals of the herbal molecules are tightly embedded in the matrix, with no herbal powder or dust produced during manufacturing. Each single dose is exact and reproducible due to the even distribution of the herbal extract.

Why Dripping Pills Increase Bioavailability?

Formation of tiny, fine crystals: In the preparation of dripping pills, herbal extract and matrix are melted together to make a solution in which the herbal extract is distributed in molecular form within the matrix. When the solution cools down the solubility decreases and the molecules of the herbal extract are separated out.

Due to rapid cooling, the viscosity of the solution increases rapidly, the solution is solidified, and the botanical molecules separated out cannot conglomerate into large crystals. As a result, micro-crystals are formed. These micro-crystals have a rapidly-dissolvable property within body fluids and a better bioavailability. For example, when Griseofulvin (an antifungal drug) Dripping Pill with PEG 6000 in its matrix is examined under a microscope, it can be seen that crystals at a size between 2-3µ account for only 5.39%, while the remaining is composed of crystals under 2µ.

Dissolubility, solubility and surface activity of the matrix: In dripping pills, the poorly soluble microcrystals of the herbal extract are surrounded tightly by a water-soluble matrix. The matrix dissolves quickly in body fluids, and the herbal extract will form a homogeneous suspension of micro-crystals when agitated slightly, allowing the herbal extract to come in contact with the body fluid closely and increase the dissolution process.

Elimination of aggregation and agglomeration of herbal extract powder: When an herbal extract with low water-solubility in powder form is put into water, some small conglomerations floating on the water surface usually occur during the course of dissolution. They are difficult to disperse, even with strong stirring. In the case of dripping pills, the tiny, fine crystals of the herbal extract are embedded in the water-soluble matrix, and thus no aggregation or agglomeration will occur. The herbal extract will become wet and begin dissolving quickly as the surrounding matrix dissolves.

As you can see, it is an intense and rigorous manufacturing process to create such an innovative new form as the dripping pill. But, when the benefits and effectiveness are so high, it seems essential to have access to such a dosage form. Honso is proud to be working with Tasly, who believes in the task of finding the most effective ways to help patients with herbal medicine, and bringing these products to the forefront of our industry worldwide.

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