Tasly was founded on May 1994. Through decades of development with Great Health industry as guideline and pharmaceutical industry as its center, Tasly has become a hi-tech group whose scope of business includes modern TCM, chemical medicine, biological medicine, healthcare products, functional food, covering the fields of research and development, planting, manufacturing and distribution. Contact:+254-723-024-871 or +254-752-520-875 Peter Mwaura
Saturday, January 12, 2008
What is heart disease ?
WHAT IS HEART DISEASE?
Heart disease is any disorder that affects the heart. Sometimes the term "heart disease" is used narrowly and incorrectly as a synonym for coronary artery disease.
Heart disease is synonymous with cardiac disease but not with cardiovascular disease which is any disease of the heart or blood vessels.
Heart disease – types of heart disease :
When you think of heart disease, usually people think of coronary artery disease (narrowing of the arteries leading to the heart), but coronary artery disease is just one type of heart disease.
Among the many types of heart disease, see, for example: Angina; Arrhythmia; Congenital heart disease; Coronary artery disease (CAD); Dilated cardiomyopathy; Heart attack (myocardial infarction); Heart failure; Hypertrophic cardiomyopathy; Mitral regurgitation; Mitral valve prolapse; and Pulmonary stenosis.
Heart disease is the leading cause of death for both men and women in the world.
Heart disease is important to learn about your to help prevent heart disease. And, if you have cardiovascular disease, you can live a healthier, more active life by learning about your heart disease and treatments and by becoming an active participant in your care.
Most famous heart disease :
Coronary Artery heart disease :
Coronary artery disease (CAD) is atherosclerosis, or hardening, of the arteries that provide vital oxygen and nutrients to the heart.
Abnormal Heart Rhythms heart disease.
The heart is an amazing organ. It beats in a steady, even rhythm, about 60 to 100 times each minute (that's about 100,000 times each day!). But, sometimes your heart gets out of rhythm. An irregular or abnormal heartbeat is called an arrhythmia. An arrhythmia heart disease (also called a dysrhythmia) can involve a change in the rhythm, producing an uneven heartbeat, or a change in the rate, causing a very slow or very fast heartbeat.
Heart disease - Heart Failure :
The term "heart failure" can be frightening. It does not mean the heart has "failed" or stopped working. It means the heart does not pump as well as it should.
Heart failure heart disease is a major health problem in the U.S., affecting nearly 5 million Americans. About 550,000 people are diagnosed with heart failure each year.
Heart disease failure is the leading cause of hospitalization in people older than 65.
Congenital Heart Disease :
Congenital heart disease is a type of defect in one or more structures of the heart or blood vessels that occur before birth. It affects about 8 out of every 1,000 children.
In this heart disease - Congenital heart defects may produce symptoms at birth, during childhood and sometimes not until adulthood.
In most cases scientists don't know why they occur. Heredity may play a role as well as exposure to the fetus during pregnancy to certain viral infections, alcohol or drugs.
Cardiomyopathies heart disease:
Cardiomyopathies heart disease are diseases of the heart muscle itself. People with cardiomyopathies heart disease have hearts that are abnormally enlarged, thickened and/or stiffened. As a result, the heart's ability to pump blood is weakened. Without treatment, cardiomyopathies worsen over time and often lead to heart failure and abnormal heart rhythms.
Aorta heart Disease and Marfan syndrome heart disease:
The aorta is the large artery that leaves the heart and provides oxygen-rich blood throughout the body.
Some conditions can cause the aorta to dilate (widen) or dissect (tear), increasing the risk for future life-threatening events
People with aorta heart disease should be treated by an experienced team of cardiovascular specialists and surgeons. Heart disease – other important terms you should know :
Heart disease - Tachycardia is an abnormally rapid beating of the heart, defined as a resting heart rate of 100 or more beats per minute in an average adult.
Heart disease - heart murmur is an extra or unusual sound heard during your heartbeat. Murmurs range from very faint to very loud and sometimes sound like a whooshing or swishing noise. Normal heartbeat sounds—"lub-DUPP" or "lub-DUB"—are the valves closing as blood moves through the heart. (Go to the How the Heart Works section for more information about how a normal heart works.)
Heart disease - Beta blockers are a class of drugs used for various indications, but particularly for the management of cardiac arrhythmias and cardioprotection after myocardial infarction.
Heart disease - Malignant hyperthermia (MH or MHS for "malignant hyperthermia syndrome", or "malignant hyperpyrexia due to anesthesia") is a life-threatening condition resulting from a genetic sensitivity of skeletal muscles to volatile anaesthetics and depolarizing neuromuscular blocking drugs that occurs during or after anaesthesia. It is related to, but distinct from, the neuroleptic malignant syndrome.
Heart disease -stent is either an expandable wire form or perforated tube (conventionally perforated by means of laser cutting) that is inserted into a natural conduit of the body to prevent or counteract a disease-induced localized flow constriction.
Heart disease - Mitral valve prolapse (MVP) is a disorder that affects one of your heart's valves — the mitral valve. It occurs when the valve doesn't close correctly, allowing backward leaking of blood in your heart.
DRUG FORM INNOVATION:
Cardiotonic Pill is made under molecule-dispersing technique, so dissolves quickly after being taken, making it more effective. Use it sublingually for a rapid absorption through sublingual vessels, higher efficacy, at the same time avoiding metabolism passage through liver.
INDICATIONS
Cardiotonic Pill can prevent and treat coronary arteriosclerosis and angina pectoris; it has effects in the vasodilatation of the coronary arteries, at the same time it has good effects on Diabetes, Hyperlipidemia, balancing HDL and LDL levels and old age related hypertension.
ACCREDITATIONS
1. Protected traditinal chinese medicine product
2. Covering most of the market in respect of Cardiovascular Disease
3. Graded as key Product in “NATIONAL MODERNIZATION MOVEMENT OF TCM”
4. First TCM Product approved by FDA IND U.S.A.
Ingredients : Radix Salviae Miltiorrhizae, Radix Notoginseng, Borneol
Specification: 250mg*30capsule/bottle
Dosage :Oral or sublingual medication, 1 to 2 capsules each time,
1 to 2 times daily before meals.
Notes :No side-effects, not to use during pregnancy.
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TASLY CARDIOTONIC PILL: IMPROVING YOUR HEART AND BLOOD MICROCIRCULATION SYSTEM
Combined with other blood moving and Qi tonifying herbs, Cardiotonic Pill or Danshen Plus Capsule is a convenient, alternative therapy for heart health based on Traditional Chinese Medicine principles and modern day research.
Its droplet pill formulation offers many advantages such as low dosage, rapid and complete absorption, fast onset of action, high potency and convenience.
Tasly Cardiotonic Pill
Main Ingredients:
Dan Shen (Salviae Mitiorrhizae)
San Qi (Panax Notoginseng)
Huang Qi (Astragalus membranaceus)
Jiang Xiang (Dalbergiae Odoriferae)
Suggested Use:
Take 1 pill orally three times per day. The effect was achieved faster when taken under the tongue, let dissolve in mouth and swallow. Improvement for healthy heart function has been seen after only 2-4 weeks.
The Dripping Pill, a Prevalent Dosage Form for Higher Bioavailability:
Innovation in herbal medicine can be found throughout the world these days, and there is no better example of manufacturing and dosage vicissitude than the dripping pill, manufactured by Tasly Pharmaceutical Co., Ltd., one of the top five largest pharmaceutical companies in China.
The Dripping Pill is a rapidly developing form of Chinese herbal medicine, prepared by blending an herbal extract and a matrix under thermal conditions and dripping the mixture into a cooling liquid in which the droplets are insoluble. The process of pill formation results in a solid-dispersoid in a pill shape.
Characteristics of the Dosage Form:
Dripping pills are a promising dosage form. The process of formation is similar to that of preparing a solid dispersoid by melting. Melting herbal extract and matrix together make the botanical molecules disperse evenly throughout the matrix, and when congealed to from a eutectic solution, both herbal extract and the matrix molecules turn into very fine, tiny crystals. These crystals are easily absorbed with a higher bioavailability, rapid biological activity and lower adverse effects compared with conventional dosage forms such as, tablets and capsules. This helps promote stability of the herbal extract. Fine crystals of the herbal molecules are tightly embedded in the matrix, with no herbal powder or dust produced during manufacturing. Each single dose is exact and reproducible due to the even distribution of the herbal extract.
Why Dripping Pills Increase Bioavailability?
Formation of tiny, fine crystals: In the preparation of dripping pills, herbal extract and matrix are melted together to make a solution in which the herbal extract is distributed in molecular form within the matrix. When the solution cools down the solubility decreases and the molecules of the herbal extract are separated out.
Due to rapid cooling, the viscosity of the solution increases rapidly, the solution is solidified, and the botanical molecules separated out cannot conglomerate into large crystals. As a result, micro-crystals are formed. These micro-crystals have a rapidly-dissolvable property within body fluids and a better bioavailability. For example, when Griseofulvin (an antifungal drug) Dripping Pill with PEG 6000 in its matrix is examined under a microscope, it can be seen that crystals at a size between 2-3µ account for only 5.39%, while the remaining is composed of crystals under 2µ.
Dissolubility, solubility and surface activity of the matrix: In dripping pills, the poorly soluble microcrystals of the herbal extract are surrounded tightly by a water-soluble matrix. The matrix dissolves quickly in body fluids, and the herbal extract will form a homogeneous suspension of micro-crystals when agitated slightly, allowing the herbal extract to come in contact with the body fluid closely and increase the dissolution process.
Elimination of aggregation and agglomeration of herbal extract powder: When an herbal extract with low water-solubility in powder form is put into water, some small conglomerations floating on the water surface usually occur during the course of dissolution. They are difficult to disperse, even with strong stirring. In the case of dripping pills, the tiny, fine crystals of the herbal extract are embedded in the water-soluble matrix, and thus no aggregation or agglomeration will occur. The herbal extract will become wet and begin dissolving quickly as the surrounding matrix dissolves.
As you can see, it is an intense and rigorous manufacturing process to create such an innovative new form as the dripping pill. But, when the benefits and effectiveness are so high, it seems essential to have access to such a dosage form. Honso is proud to be working with Tasly, who believes in the task of finding the most effective ways to help patients with herbal medicine, and bringing these products to the forefront of our industry worldwide.
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